Home-to-lab testing allows individuals to collect samples comfortably at home. The main advantages of home sampling include convenience, privacy, and accessibility, as individuals can perform the tests at their own convenience.

Once the sample is collected, it is sent to our laboratory for analysis from anywhere in the world. You will be notified on your registered email once the results are ready, and can be downloaded from your registered account.

DBS testing is no more painful than a self-prick for a glucometer test. The kit contains one-time-use safety lancets which are used for pricking a finger and depositing a sample on a special filter paper card. The blood spot deposited on the filter paper card is allowed to dry, and hence the name dried blood spot.

Similarly, some tests may require saliva, urine or stool samples, which can also be collected on special filter paper cards. This makes the sample collection completely non-invasive.

Watching the instructional video and carefully reading the instruction manual before conducting the test should ensure a smooth experience. Should you encounter any difficulties, please do not hesitate to contact us for assistance.

Once we receive your sample, the average response time is 7-10 business days to receive the results.

Lipomic LifeSciences can provide evidence-based suggestions for lifestyle changes that you can make to positively impact your health. We can also connect you with leading medical experts who can guide and discuss potential next steps.

Menstruating women should collect the sample one week after ovulation, usually between days 19-23 of a normal cycle. Women in menopause can collect the sample at any time of the month.

Estrogen is a group of steroid hormones essential for the development and regulation of the female reproductive system and secondary sexual characteristics. The three main types of estrogen are estradiol, estrone, and estriol. Estradiol is the most potent and prevalent form during reproductive years, estrone is the primary form after menopause, and estriol is predominantly produced during pregnancy.

This test measures estradiol, also known as E2, is the most potent and prevalent form of estrogen in the human body, particularly in women of reproductive age. It is primarily produced by the ovaries, though smaller amounts are also synthesized in the adrenal glands, fat tissues, and during pregnancy, the placenta.

Key roles and functions of estradiol include:

1. Reproductive Function: Estradiol plays a central role in the menstrual cycle. It helps regulate the growth of the uterine lining (endometrium) during the first half of the cycle, preparing it for potential implantation of a fertilized egg.
2. Secondary Sexual Characteristics: Estradiol contributes to the development of secondary sexual characteristics in females, such as breast development, widening of the hips, and distribution of body fat.
3. Bone Health: Estradiol is essential for maintaining bone density. It promotes the activity of osteoblasts (cells that build bone) and inhibits osteoclasts (cells that break down bone), thereby reducing the risk of osteoporosis.
4. Cardiovascular Health: Estradiol has protective effects on the cardiovascular system. It helps maintain healthy blood vessel function and improves lipid profiles, which can lower the risk of heart disease.
5. Brain Function: Estradiol influences mood, cognition, and memory. It plays a role in maintaining emotional well-being and cognitive function.
6. Skin and Hair: Estradiol contributes to skin hydration, thickness, and elasticity. It also affects hair growth and health.

Throughout a woman’s life, estradiol levels fluctuate, reaching peak levels during the reproductive years and declining during menopause. Changes in estradiol levels can lead to symptoms like hot flashes, mood swings, vaginal dryness, and changes in menstrual patterns.

Symptoms of Estradiol Deficiency

Estrogen deficiency, often occurring during menopause or due to other medical conditions, can lead to a variety of symptoms. Here are some common signs of low estrogen levels:

1. Hot Flashes and Night Sweats: Sudden feelings of heat, often accompanied by sweating and a flushed appearance, especially at night.
2. Irregular Periods: Changes in menstrual cycle frequency, duration, or flow. Periods may become lighter, heavier, or less regular.
3. Vaginal Dryness: Reduced lubrication in the vaginal area, leading to discomfort, itching, and painful intercourse.
4. Mood Swings and Depression: Increased feelings of irritability, anxiety, and depression.
5. Sleep Problems: Difficulty falling asleep or staying asleep, often due to night sweats.
6. Decreased Libido: Reduced interest in sexual activity.
7. Memory and Concentration Issues: Difficulty focusing, forgetfulness, and brain fog.
8. Bone Density Loss: Increased risk of osteoporosis and fractures due to decreased bone strength.
9. Fatigue: Persistent tiredness and lack of energy.
10. Skin Changes: Dry, thin, or sagging skin.
11. Urinary Issues: Increased frequency of urinary tract infections (UTIs) and urinary incontinence.

These symptoms can vary in intensity and may not all be present in every individual experiencing estrogen deficiency. If you suspect you have low estrogen levels, it’s important to consult a healthcare provider for proper diagnosis and treatment options.

Pg is a hormone essential for regulating the menstrual cycle and maintaining pregnancy. Produced mainly in the ovaries after ovulation, it prepares the uterus for a potential pregnancy by thickening its lining. If pregnancy does not occur, Pg levels drop, leading to menstruation. During pregnancy, Pg supports the developing baby and prevents early contractions.

Beyond reproduction, Pg affects breast development, mood, sleep, bone density, and heart health. Medically, it’s used in hormone replacement therapy to relieve menopause symptoms and in birth control methods to prevent ovulation. Imbalances in Pg can cause irregular menstrual cycles, fertility issues, mood swings, and anxiety.

Pg deficiency symptoms

Pg deficiency, often occurring during certain phases of the menstrual cycle, perimenopause, or due to medical conditions, can lead to various symptoms. Here are some common signs of low Pg levels:

1. Irregular Menstrual Cycles: Changes in the length, timing, or flow of menstrual periods.
2. Heavy Menstrual Bleeding: Menstrual periods that are unusually heavy or prolonged.
3. Difficulty Getting Pregnant: Reduced fertility due to irregular ovulation or inadequate preparation of the uterine lining for implantation.
4. Premenstrual Syndrome (PMS): Increased mood swings, irritability, anxiety, or depression in the days leading up to menstruation.
5. Hot Flashes: Sudden feelings of heat, similar to those experienced during menopause.
6. Insomnia: Difficulty falling asleep or staying asleep, often related to hormonal fluctuations.
7. Low Libido: Reduced interest in sexual activity.
8. Fatigue: Persistent tiredness and lack of energy.
9. Headaches: Particularly migraines that may worsen around the time of menstruation.
10. Vaginal Dryness: Reduced lubrication and discomfort during intercourse.
11. Breast Tenderness: Increased sensitivity or pain in the breasts.
12. Digestive Issues: Bloating, constipation, or diarrhea, often related to hormonal imbalances.

These symptoms can vary in severity and may not all be present in every individual experiencing Pg deficiency.

For pregnant females, it is crucial for a successful pregnancy to sustain high levels of Pg. Low levels of Pg can cause pregnancy complications such as miscarriage or preterm labour.

The Pg/E2 ratio is helpful in clinical practice when both Pg and E2 are within range, yet the patient continues to have symptoms. The interpretation of the Pg/E2 ratio depends on the phase of the menstrual cycle, the clinical context, and the individual’s baseline hormone levels.

Assessment of Ovulation and Luteal Phase Function

• During the menstrual cycle, Pg and estradiol levels fluctuate. A high Pg/E2 ratio in the luteal phase (after ovulation) typically indicates normal ovulation and proper luteal phase function, as Pg becomes dominant during this time. A Pg/E2 indicate luteal phase defects, anovulation, or inadequate corpus luteum function.

Fertility Monitoring

• In assisted reproductive technologies (ART) like IVF, the Pg/E2 ratio helps evaluate ovarian response to stimulation and endometrial receptivity. An abnormal ratio can signal poor ovarian response or an imbalance that may hinder implantation.

Hormonal Imbalance Diagnosis

• Conditions like Polycystic Ovary Syndrome (PCOS), menopause, or other endocrine disorders can cause deviations in the P/E2 ratio. A high E2 and low Pg ratio may suggest estrogen dominance, common in PCOS or perimenopause.

Pregnancy Support

• A balanced Pg/E2 ratio is crucial for maintaining a healthy pregnancy in early stages. Monitoring these levels can help assess the risk of miscarriage or implantation failure.

Cancer Risk and Hormonal Disorders

• An abnormal ratio can be a marker for certain hormone-sensitive cancers (e.g., breast or endometrial cancer) or indicate hormone-related disorders.